DENTAL group Q& M  Q& M Dental: QC7 +1.61%  on Friday (Dec 3) announced that polymerase chain reaction (PCR) test kits developed by its subsidiary, Acumen Diagnostics, are capable of detecting Covid-positive cases of the new variant Omicron.

In addition to the Delta variant, the home-grown medical technology company' s 2 PCR test kits, Acu-Corona 2.0 and Acu-Corona Duplex, can also detect Omicron.

As the PCR test kits are locally manufactured, they can be deployed quickly and more efficiently. Q& M Dental Group has highlighted Acumen' s cost-effectiveness and greater self-sufficiency compared to that of its peers imported from overseas.

Acumen currently operates 2 laboratories that can process 7,000 diagnostic tests on a daily basis.

Ong Siew Hwa, executive director of Aoxin Q& M Dental, and chief executive officer and chief scientist of Acumen Diagnostics, is confident of Acumen' s PCR tests in detecting the new, highly infectious variant.

She said: " With PCR tests remaining the gold standard to detect Covid-19, Acumen remains well-positioned to help Singapore tackle this new challenge posed by the virus, with our effective and affordable PCR test kits that are equipped to detect Covid-19 positive cases infected with Delta and Omicron, as well as our laboratory testing capabilities that can run 7,000 tests daily."

Acumen is a 51 per cent-owned subsidiary of Q& M and 49 per cent owned by Aoxin Q& M  $ Aoxin Q & M: 1D4 +2.08%. It is one of the few companies in Singapore with proprietary technology in testing for Covid-19.

SINGAPORE - The battle to fend off the  new Omicron coronavirus variant has got a boost from polymerase chain reaction (PCR) test kits developed by home-grown medical technology firm Acumen Diagnostics.

Its two PCR test kits - Acu-Corona 2.0 and Acu-Corona Duplex - which can detect the Delta variant, can  also identify the Omicron strain. These kits are already in use.

It was reported on Thursday (Dec 2) that two imported Covid-19 cases have preliminarily tested positive for the Omicron variant in Singapore.

The Acu-Corona 2.0 test  targets  two Covid-19 genes - RdRp and E - that are present in both the Omicron and Delta variants.

Meanwhile, the Acu-Corona Duplex test targets the E gene and S gene. The portion of the S gene targeted by the test does not contain any of the 32 mutations in the Omicron variant, hence it can detect the  variant without any loss of sensitivity.

Omicron  has a large number of gene mutations that have  not been reported in a single viral variant before. So far, scientists have seen 32 mutations in the spike gene of Omicron, whereas there are nine mutations in Delta' s spike gene, and this  gives them  reason to believe that Omicron may have fairly different characteristics from  previous variants.

The spike protein is an important part of the virus that allows it to bind to human cells and facilitate infection of the cells. So a change in the spike protein may change the ability of the virus to infect cells and cause adverse effects.

Acumen Diagnostics said on Friday that since the kits are manufactured locally, they  can be deployed quickly and cost about half the price of imported ones.

The firm currently operates two laboratories that can process 7,000 diagnostic tests daily.

Dr Ong Siew Hwa, Acumen Diagnostics' chief executive officer and chief scientist, said: " With PCR tests remaining the gold standard to detect Covid-19, Acumen Diagnostics remains well positioned to help Singapore tackle this new challenge posed by the virus."

Acumen Diagnostics is not the only firm whose existing kits are capable of detecting Omicron.

Biotech firm MiRXES, which is currently using its Fortitude 2.1 Covid-19 PCR kit in Singapore, has also said the kit  can detect all Sars-CoV-2 variants of concern identified so far, including  Delta and Omicron.

Local biotech company BioAcumen Global also said the  new variant does not affect the detection capability of its existing kit, the BioA  SARS-CoV-2 Real-Time RT-PCR kit v2.0. 

All these kits detect both Delta and Omicron, but are not able to distinguish between the two. To confirm if a positive Covid-19 case has been infected by the Omicron variant, gene sequencing is necessary.

A preliminary study by South African scientists published on Thursday  suggests that the Omicron variant is three times more likely to cause reinfections compared with the Delta or Beta strain.

The spread of Omicron  has upset the reopening of travel in many countries.

In Singapore,  tighter border measures  took effect from 11.59pm on Thursday, and three planned  vaccinated travel lanes for Qatar, Saudi Arabia and the United Arab Emirates have been postponed indefinitely. 

Malaysia has  temporarily banned the entry of travellers from countries that have reported the Omicron variant or are considered high-risk. The travel ban so far applies to eight African countries, including South Africa, Zimbabwe, Mozambique and Malawi, but this could be extended to other places where the variant has been detected.